Raekil Park Selected Research

Ototoxicity

1/2018	Protective roles of fenofibrate against cisplatin-induced ototoxicity by the rescue of peroxisomal and mitochondrial dysfunction.
4/2017	Fenofibrate exerts protective effects against gentamicin-induced toxicity in cochlear hair cells by activating antioxidant enzymes.
1/2017	Interleukin-10 Attenuates Hypochlorous Acid-Mediated Cytotoxicity to HEI-OC1 Cochlear Cells.
4/2016	3-Aminotriazole protects from CoCl2-induced ototoxicity by inhibiting the generation of reactive oxygen species and proinflammatory cytokines in mice.
3/2016	Dunnione ameliorates cisplatin ototoxicity through modulation of NAD(+) metabolism.
11/2015	Dunnione ameliorates cisplatin-induced small intestinal damage by modulating NAD(+) metabolism.
10/2015	Erdosteine protects HEI-OC1 auditory cells from cisplatin toxicity through suppression of inflammatory cytokines and induction of Nrf2 target proteins.
8/2015	Nicotinamide adenine dinucleotide: An essential factor in preserving hearing in cisplatin-induced ototoxicity.
2/2015	Bucillamine prevents cisplatin-induced ototoxicity through induction of glutathione and antioxidant genes.
6/2014	Activation of β-catenin by inhibitors of glycogen synthase kinase-3 ameliorates cisplatin-induced cytotoxicity and pro-inflammatory cytokine expression in HEI-OC1 cells.

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Raekil Park Research Topics

Disease

20	Ototoxicity 01/2018 - 09/2007
15	Neoplasms (Cancer) 11/2018 - 10/2002
11	Mitochondrial Diseases (Mitochondrial Disease) 06/2019 - 06/2004
10	Hearing Loss (Hearing Impairment) 04/2017 - 01/2011
7	Inflammation (Inflammations) 12/2018 - 11/2008
5	Insulinoma 02/2009 - 04/2007
5	Cerebral Infarction 09/2008 - 05/2007
4	Obesity 01/2017 - 01/2013
3	Hepatocellular Carcinoma (Hepatoma) 08/2010 - 06/2004
3	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 02/2009 - 04/2007
3	Lung Neoplasms (Lung Cancer) 04/2008 - 06/2006
2	Acatalasia (Acatalasemia) 12/2021 - 01/2021
2	Auditory neuropathy 06/2019 - 08/2008
2	Pancreatitis 12/2018 - 01/2017
2	Starvation 01/2018 - 12/2013
2	Weight Gain 01/2017 - 01/2016
2	Tinnitus 01/2013 - 06/2005
2	Glioblastoma (Glioblastoma Multiforme) 01/2010 - 04/2008
2	Otitis Media 07/2007 - 06/2006
1	Heart Failure 11/2018
1	Cardiotoxicity 11/2018
1	Neoplasm Metastasis (Metastasis) 01/2017
1	Melanoma (Melanoma, Malignant) 01/2017
1	Colorectal Neoplasms (Colorectal Cancer) 10/2016
1	Hemorrhage 09/2016
1	Peripheral Nervous System Diseases (PNS Diseases) 04/2016
1	Pulmonary Fibrosis (Fibrosing Alveolitis) 04/2016
1	Deaf-Blind Disorders 04/2016

Drug/Important Bio-Agent (IBA)

20	Cisplatin (Platino)FDA LinkGeneric 01/2018 - 06/2005
14	CytokinesIBA 01/2017 - 06/2006
9	Proteins (Proteins, Gene)FDA Link 11/2018 - 10/2005
7	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 03/2010 - 08/2003
6	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2021 - 01/2010
6	CaspasesIBA 04/2008 - 02/2002
5	NAD (NADH)IBA 11/2018 - 03/2014
5	Interleukin-6 (Interleukin 6)IBA 03/2010 - 05/2007
4	Messenger RNA (mRNA)IBA 11/2018 - 05/2007
4	Caspase 3 (Caspase-3)IBA 01/2012 - 06/2004
4	Caspase 9IBA 01/2010 - 06/2004
4	Cytochromes c (Cytochrome c)IBA 04/2007 - 06/2004
3	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2018 - 01/2013
3	Fenofibrate (CiL)FDA LinkGeneric 01/2018 - 12/2013
3	Interleukin-10 (Interleukin 10)IBA 01/2017 - 06/2007
3	InterleukinsIBA 06/2008 - 06/2007
2	CatalaseIBA 01/2021 - 01/2018
2	dunnioneIBA 12/2018 - 03/2016
2	NADPH Oxidases (NAD(P)H oxidase)IBA 12/2018 - 03/2010
2	EnzymesIBA 12/2018 - 02/2009
2	Doxorubicin (Adriamycin)FDA LinkGeneric 11/2018 - 10/2002
2	Heme Oxygenase-1IBA 01/2017 - 04/2008
2	beta-lapachoneIBA 01/2017 - 03/2014
2	Antineoplastic Agents (Antineoplastics)IBA 01/2017 - 01/2008
2	Mitogen-Activated Protein KinasesIBA 01/2017 - 10/2005
2	RNA Splicing FactorsIBA 10/2016 - 10/2014
2	AntioxidantsIBA 01/2016 - 02/2015
2	Triglycerides (Triacylglycerol)IBA 01/2016 - 12/2013
2	Pharmaceutical PreparationsIBA 11/2015 - 02/2002
2	DNA AdductsIBA 03/2014 - 09/2007
2	Gentamicins (Gentamicin)FDA LinkGeneric 10/2013 - 03/2013
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2012 - 11/2007
2	S-Nitroso-N-AcetylpenicillamineIBA 01/2012 - 04/2007
2	Interleukin-1beta (Interleukin 1 beta)IBA 03/2010 - 09/2008
2	BerberineIBA 01/2010 - 04/2008
2	Streptozocin (Streptozotocin)FDA Link 02/2009 - 10/2008
2	LipopolysaccharidesIBA 09/2008 - 06/2008
2	SasimIBA 09/2008 - 05/2007
2	NF-kappa B (NF-kB)IBA 09/2008 - 04/2008
2	FlunarizineIBA 09/2008 - 06/2005
2	PhytohemagglutininsIBA 06/2008 - 05/2007
2	Benzo(a)pyreneIBA 12/2005 - 06/2004
1	Nonesterified Fatty Acids (NEFA)IBA 12/2021
1	Pyridoxine (Pyridoxin)FDA LinkGeneric 06/2019
1	CeruletideIBA 12/2018
1	NADP (NADPH)IBA 12/2018
1	Biomarkers (Surrogate Marker)IBA 11/2018
1	Small Interfering RNA (siRNA)IBA 01/2018
1	Anti-Bacterial Agents (Antibiotics)IBA 04/2017
1	AminoglycosidesIBA 04/2017
1	FarnesolIBA 01/2017
1	InflammasomesIBA 01/2017
1	Terpenes (Terpenoids)IBA 01/2017
1	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 01/2017
1	albiflorinIBA 01/2017
1	Hypochlorous Acid (Hypochlorite)IBA 01/2017
1	MorpholinosIBA 12/2016
1	CobaltIBA 04/2016
1	Sirtuin 1IBA 03/2016
1	Poly (ADP-Ribose) Polymerase-1IBA 03/2016
1	AMP-Activated Protein KinasesIBA 01/2016
1	arctigeninIBA 01/2016
1	tetrabromobisphenol AIBA 01/2016
1	Fatty Acid Synthases (Fatty Acid Synthase)IBA 01/2016
1	Fatty Acid-Binding ProteinsIBA 01/2016
1	Lipoprotein Lipase (Diacylglycerol Lipase)IBA 01/2016

Therapy/Procedure

8	East Asian Traditional Medicine (Oriental Medicine) 06/2010 - 02/2002
7	Drug Therapy (Chemotherapy) 11/2018 - 01/2011
5	Therapeutics 04/2017 - 10/2007
2	Intratympanic Injection 04/2015 - 10/2013
1	Transplantation 09/2016
1	Oral Administration 01/2016